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Mark A. Metzke is an associate in our Washington D.C. office. He practices intellectual property law, with an emphasis in patent prosecution and litigation in the chemical and life sciences fields.
Prior to joining the firm, Dr. Metzke worked as a scientist at the Hitachi Chemical Research Center, where he performed research in the area of synthetic biomaterials. Before becoming a scientist, Dr. Metzke worked as a research chemist for Pharm-Eco Laboratories (now Johnson Matthey Pharma Services, Inc.). At Pharm-Eco, Dr. Metzke worked in the area of process development.
Dr. Metzke earned his Ph.D. from at the University of California, Irvine, where his research in the Organic Chemistry Department concentrated on biomaterials. His projects involved synthesizing small-molecule-monomers derived from peptides and saccharides and polymerizing these monomers to afford new classes of biomaterials. Dr. Metzke also tested these biomaterials to determine their suitability in tissue engineering and drug/gene delivery applications.
Dr. Metzke joined the firm in 2011.
Specializing In
Cases, Articles, Speeches & Seminars
Articles and Presentations
Dr. Mark Metzke (panelist), “Biotech Showcase,” Phacilitate; Cell and Gene Therapy World, Washington, DC (January 26, 2016).
Dr. Mark Benedict and Dr. Mark Metzke, Featured in "Patent a Cure for the Common Cold? This Lawyer Did," Corporate Counsel (2015).
Jonathan Bachand and Dr. Mark Metzke, Complex Litigation for Complex Molecules: An Introduction to the Biologics Price Competition and Innovation Act, 14 Orange County ABTL Report 3 (2012).
Mark Metzke, Increasing Follow-On Biologics Competition with a New Biologics Act, 39 AIPLA Q.J. 357 (2011).
Mark Metzke, Targeting Enantiomer Product Hopping with a New “Obviousness” Standard, 14 UCLA J.L. & Tech. 1 (2010).
Mark Metzke & Zhibin Guan, Synthesis and Structure-Property Investigation of a Family of Carbohydrate-Derived Polyesters and Polyamides as Biomaterials, 9 Biomacromolecules 208 (2008).
Chirag B. Khatiwala, Shelly R. Peyton, Mark Metzke, & Andrew J. Putnam, The Regulation of Osteogenesis by ECM Rigidity in MC3T3-E1 Cells Requires MAPK Activation, 211 J. Cell Physiology 661 (2007).
Mark Metzke, Naphtali O'Connor, Soumen Maiti, & Zhibin Guan, New class of biomaterials made from natural building blocks: Saccharide-peptide hybrid copolymers, 95 PMSE Preprints 1058 (2006).
Mark Metzke, Novel Biomaterials from Natural Building Blocks, International Symposium on LifeChips, Irvine, CA (2006).
Mark Metzke, Naphtali O'Connor, Soumen Maiti, Ed Nelson & Zhibin Guan, Saccharide-Peptide Hybrid Copolymers as a New Class of Biomaterials, 44 Angewandte Chemie Int. Edition 6529 (2005). Highlighted in 83 Chem. & Eng’g News “Latest News” (2005).
Mark Metzke, Jane Z. Bai, & Zhibin Guan, Structure-property correlation for carbohydrate-derived side-chain polyethers as new protein-resistant biomaterials, 46 Polymer Preprints 325, (2005).
Mark Metzke, Naphtali O'Connor, Soumen Maiti, & Zhibin Guan, Carbohydrate-peptide hybrid copolymers as safe and effective gene delivery vectors, 92 PMSE Preprints 648, (2005).
Mark Metzke, Novel Biomaterials from Natural Building Blocks, Project T2: A Technology Transfer Conference, Los Angeles, CA, (Nov. 8, 2005).
Mark Metzke, Novel Biomaterials from Natural Building Blocks, Gordon Research Conference, Plymouth, NH, (Aug. 2005).
Mark Metzke, Structure-property correlation for carbohydrate-derived side-chain polyethers as new protein-resistant biomaterials, 229th ACS National Meeting, San Diego, CA, (Mar. 2005).
Mark Metzke, Carbohydrate-peptide hybrid copolymers as safe and effective gene delivery vectors, 229th ACS National Meeting, San Diego, CA, (Mar. 2005).
Mark Metzke, Jane Z. Bai, & Zhibin Guan, Protein resistant carbohydrate-derived side-chain polyethers, 45 Polymer Preprints 101, (2004).
Mark Metzke, Jane Z. Bai, & Zhibin Guan, A Novel Carbohydrate-Derived Side-Chain Polyether with Excellent Protein Resistance, 125 J. Am. Chem. Soc’y 7760, (2003). Highlighted in 301 Science 279, (2003).
Mark Metzke, Developing Carbohydrate-Based Side-Chain Polyethers as New Biomaterial for Protein Resistance and Tissue Engineering, MRS Fall Meeting, Boston, MA, (Winter 2003).
Professional Memberships
American Association for Clinical Chemistry
American Chemical Society
Materials Research Society
Nano Science and Technology Institute
Orange County Patent Law Association
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